Article
Leptin concentrations, leptin receptor polymorphisms, and colorectal adenoma risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2007
Chia Victoria M, Newcomb Polly A, Lampe Johanna W, White Emily, Mandelson Margaret T, McTiernan Anne, Potter John D
Abstract excerpt
Obesity has been shown to be associated with an increased risk of both colorectal cancer and adenomatous polyps. One mechanism underlying this relationship may involve the growth-promoting effects of the circulating hormones associated with obesity, such as leptin. We conducted a gastroenterology...
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