Article
Leveraging epigenomics and contactomics data to investigate SNP pairs in GWAS.
Human genetics - 1 May 2018
Manduchi Elisabetta, Williams Scott M, Chesi Alessandra, Johnson Matthew E, Wells Andrew D, Grant Struan F A, Moore Jason H
Abstract excerpt
Although Genome Wide Association Studies (GWAS) have led to many valuable insights into the genetic bases of common diseases over the past decade, the issue of missing heritability has surfaced, as the discovered main effect genetic variants found to date do not account for much of a trait's predicted genetic component. We present a workflow, integrating epigenomics and topologically associating domain data,...
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