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The Human Serotonin Type 3 Receptor Gene (HTR3A-E) Allelic Variant Database.

Human mutation - 1 Feb 2017

Celli Jacopo, Rappold Gudrun, Niesler Beate

Abstract excerpt

Serotonin type 3 (5-HT3 ) receptors are ligand-gated ion channels formed by five subunits (5-HT3A-E), which are encoded by the HTR3A, HTR3B, HTR3C, HTR3D, and HTR3E genes. Functional receptors are pentameric complexes of diverse composition. Different receptor subtypes confer a predisposition to nausea and vomiting during chemotherapy, pregnancy, and following surgery. In addition, different subtypes contribute...

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Identifiers

PMID: 27763704
DOI: 10.1002/humu.23136

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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