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Article

Serotonin type 3 receptor genes: HTR3A, B, C, D, E.

Pharmacogenomics - 1 May 2008

Niesler Beate, Kapeller Johannes, Hammer Christian, Rappold Gudrun

Abstract excerpt

The 5-HT(3) receptor is a ligand-gated ion channel composed of five subunits. To date, five different human subunits are known, 5-HT(3AE), which are encoded by the serotonin receptor genes HTR3A, HTR3B, HTR3C, HTR3D and HTR3E, respectively. Functional receptors are pentameric complexes of diverse composition. Different receptor subtypes seem to be involved in chemotherapy-induced nausea and vomiting (CINV),...

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PMID: 18466097
DOI: 10.2217/14622416.9.5.501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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