Presence of Human Papillomavirus (HPV) Apolipoprotein B Messenger RNA Editing, Catalytic Polypeptide-Like 3 (APOBEC)-Related Minority Variants in HPV-16 Genomes From Anal and Cervical Samples but Not in HPV-52 and HPV-58.

doi:10.1093/infdis/jiy287

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Presence of Human Papillomavirus (HPV) Apolipoprotein B Messenger RNA Editing, Catalytic Polypeptide-Like 3 (APOBEC)-Related Minority Variants in HPV-16 Genomes From Anal and Cervical Samples but Not in HPV-52 and HPV-58.

The Journal of infectious diseases - 24 Aug 2018

Mariaggi Alice-Andrée, Péré Hélène, Perrier Marine, Visseaux Benoit, Collin Gilles, Veyer David, Le Hingrat Quentin, Ferré Valentine Marie, Joly Véronique, Couvelard Anne, Bucau Margot, Davitian Carine, Descamps Diane, Abramowitz Laurent, Charpentier Charlotte

Abstract excerpt

Background: The aim of this study was to investigate the presence of minority variants (MVs) in high-risk human papillomavirus (HPV) types (HPV-16, -52, and -58) from cervical and anal smears. Methods: Whole HPV genome ultra-deep sequencing (UDS) was performed on cervical and anal smears collected during patient follow-up. Bioinformatics analyses were performed using Bowtie2 (Geneious). Results: We assessed 55...

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PMID: 29788374
DOI: 10.1093/infdis/jiy287

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