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Interplay of strain and race/ethnicity in the innate immune response to M. tuberculosis

22 May 2018

Abstract excerpt

BACKGROUND: The roles of host and pathogen factors in determining innate immune responses to M. tuberculosis are not fully understood. In this study, we examined host macrophage immune responses of 3 race/ethnic groups to 3 genetically and geographically diverse M. tuberculosis lineages. METHODS: Monocyte-derived macrophages from healthy Filipinos, Chinese and non-Hispanic White study participants (approximately...

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PMID: 29787561
DOI: 10.1371/journal.pone.0195392

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