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Article

Ethnicity and mycobacterial lineage as determinants of tuberculosis disease phenotype.

Thorax - 1 Mar 2013

Pareek Manish, Evans Jason, Innes John, Smith Grace, Hingley-Wilson Suzie, Lougheed Kathryn E, Sridhar Saranya, Dedicoat Martin, Hawkey Peter, Lalvani Ajit

Abstract excerpt

BACKGROUND: Emerging evidence suggests that Mycobacterium tuberculosis (Mtb) lineage and host ethnicity can determine tuberculosis (TB) clinical disease patterns but their relative importance and interaction are unknown. METHODS: We evaluated prospectively collected TB surveillance and Mtb strain typing data in an ethnically heterogeneous UK population. Lineage assignment was denoted using 15-loci mycobacterial...

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PMID: 23019255
DOI: 10.1136/thoraxjnl-2012-201824
PMCID: PMC5741171

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