Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The degree of HIV-1 amino acid variability is strictly related to different disease progression rates.

Virus genes - 1 Aug 2018

Scutari Rossana, Faieta Monica, D'Arrigo Roberta, Fabeni Lavinia, Mussini Cristina, Cossarizza Andrea, Casoli Claudio, Perno Carlo Federico, Svicher Valentina, Alteri Claudia, Aquaro Stefano

Abstract excerpt

The aim of this study is to evaluate the amino acid variability of HIV-1 Gp41, C2-V3, and Nef in a group of patients characterized by different disease progression rates. HIV-1 sequences were collected from 19 Long term non progressor patients (LTNPs), 9 slow progressors (SPs), and 11 rapid progressors (RPs). Phylogenetic trees were estimated by MEGA 6. Differences in amino acid variability among sequences...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4 Lymphocyte Count
Share to Epitopes, T-Lymphocyte

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp41

Share to HIV Infections

Share to Peptides

Share to T-Lymphocytes, Cytotoxic

Share to Viral Load

Source

Identifiers

PMID: 29777446
DOI: 10.1007/s11262-018-1571-2

Genes

C2
CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The degree of HIV-1 amino acid variability is strictly related to different disease progression rates.PMID 29777446Read ↗

The characteristics of the HIV-1 Env glycoprotein contribute to viral pathogenesisSemantic proximity Read ↗

Host and Viral Genetic Correlates of Clinical Definitions of HIV-1 Disease ProgressionSemantic proximity Read ↗

Sequence heterogeneity in human immunodeficiency virus type 1 nef in patients presenting with rapid progression and delayed progression to AIDS.Semantic proximity Read ↗

An Observational Study of Genetic Diversity of HIV-1 vpu in Rapid Progressors in India.Semantic proximity Read ↗

The Characteristics of the HIV-1 Env Glycoprotein Are Linked With Viral PathogenesisSemantic proximity Read ↗

Dynamic features of the selective pressure on the human immunodeficiency virus type 1 (HIV-1) gp120 CD4-binding site in a group of long term non progressor (LTNP) subjects.Semantic proximity Read ↗

Nef HIV-1 (Retroviridae: Orthoretrovirinae: Lentivirus: Human immunodeficiency virus-1), multifunctional protein: features of genetic virus variants circulating in Russia.Semantic proximity Read ↗

Evolution of human immunodeficiency virus type 1 env sequence variation in patients with diverse rates of disease progression and T-cell function.Semantic proximity Read ↗

The CpG dinucleotide content of the HIV-1 envelope gene may predict disease progressionSemantic proximity Read ↗

In vivo sequence variability of human immunodeficiency virus type 1 envelope gp120: association of V2 extension with slow disease progression.Semantic proximity Read ↗

Different HIV-1 env frames: gp120 and ASP (antisense protein) biosynthesis, and theirs co-variation tropic amino acid signatures in X4- and R5-viruses.Semantic proximity Read ↗

Baseline CD4+ T cell counts correlates with HIV-1 synonymous rate in HLA-B*5701 subjects with different risk of disease progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.