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The CpG dinucleotide content of the HIV-1 envelope gene may predict disease progression

9 Aug 2017

Abstract excerpt

The clinical course of HIV-1 varies greatly among infected individuals. Despite extensive research, virus factors associated with slow-progression remain poorly understood. Identification of unique HIV-1 genomic signatures linked to slow-progression remains elusive. We investigated CpG dinucleotide content in HIV-1 envelope gene as a potential virus factor in disease progression. We analysed 1808 HIV-1 envelope...

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PMID: 28811638
DOI: 10.1038/s41598-017-08716-1

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