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Article

Baseline CD4+ T cell counts correlates with HIV-1 synonymous rate in HLA-B*5701 subjects with different risk of disease progression.

PLoS computational biology - 1 Sept 2014

Norström Melissa M, Veras Nazle M, Huang Wei, Proper Mattia C F, Cook Jennifer, Hartogensis Wendy, Hecht Frederick M, Karlsson Annika C, Karlsoon Annika C, Salemi Marco

Abstract excerpt

HLA-B*5701 is the host factor most strongly associated with slow HIV-1 disease progression, although risk of progression may vary among patients carrying this allele. The interplay between HIV-1 evolutionary rate variation and risk of progression to AIDS in HLA-B*5701 subjects was studied using longitudinal viral sequences from high-risk progressors (HRPs) and low-risk progressors (LRPs). Posterior distributions...

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Identifiers

PMID: 25187947
DOI: 10.1371/journal.pcbi.1003830
PMCID: PMC4154639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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