Article
Deltex interacts with Eiger and consequently influences the cell death in Drosophila melanogaster.
Cellular signalling - 1 Sept 2018
Dutta Debdeep, Singh Ankita, Paul Maimuna Sali, Sharma Vartika, Mutsuddi Mousumi, Mukherjee Ashim
Abstract excerpt
TNF-JNK signaling is one of the highly conserved signaling pathways that regulate a broad spectrum of cellular processes including proliferation and apoptosis. Eiger, the sole homologue of TNF in Drosophila, initiates the TNF-JNK pathway to induce cell death. Previously, Deltex (Dx) has been identified as a Notch signaling component that regulates vesicular trafficking of Notch. In the present study, we have...
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