Article
Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling.
The Journal of biological chemistry - 9 Aug 2002
Kanda Hiroshi, Igaki Tatsushi, Kanuka Hirotaka, Yagi Takeshi, Miura Masayuki
Abstract excerpt
We identified Wengen, the first member of the Drosophila tumor necrosis factor receptor (TNFR) superfamily. Wengen is a type III membrane protein with conserved cysteine-rich residues (TNFR homology domain) in the extracellular domain, a hallmark of the TNFR superfamily. wengen mRNA is expressed at all stages of Drosophila development. The small-eye phenotype caused by an eye-specific overexpression of a...
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