Article
Snail modulates JNK-mediated cell death in Drosophila.
Cell death & disease - 26 Nov 2019
Wu Chenxi, Li Zhuojie, Ding Xiang, Guo Xiaowei, Sun Ying, Wang Xingjun, Hu Yujia, Li Tongtong, La Xiaojin, Li Jianing, Li Ji-An, Li Wenzhe, Xue Lei
Abstract excerpt
Cell death plays a pivotal role in animal development and tissue homeostasis. Dysregulation of this process is associated with a wide variety of human diseases, including developmental and immunological disorders, neurodegenerative diseases and tumors. While the fundamental role of JNK pathway in cell death has been extensively studied, its down-stream regulators and the underlying mechanisms remain largely...
Topics
- Animals
- Apoptosis
- Drosophila Proteins
- Drosophila melanogaster
- Eye
- Genes, Dominant
- Genetic Testing
- JNK Mitogen-Activated Protein Kinases
- Larva
- MAP Kinase Signaling System
- Phenotype
- Snail Family Transcription Factors
- Transcription, Genetic