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Article

Epithelial proliferation in inflammatory skin disease is regulated by tetratricopeptide repeat domain 7 (Ttc7) in fibroblasts and lymphocytes.

The Journal of allergy and clinical immunology - 1 Jan 2019

Nüesch Ursina, Mauracher Andrea A, Opitz Lennart, Volkmer Benjamin, Michalak-Mićka Katarzyna, Kamarashev Jivko, Hartwig Tom, Reichmann Ernst, Becher Burkhard, Vavassori Stefano, Pachlopnik Schmid Jana

Abstract excerpt

BACKGROUND: Mutations in tetratricopeptide repeat domain 7A (TTC7A) and its mouse orthologue, Ttc7, result in a multisystemic disease, mostly affecting the epithelial barriers and immune system. Despite successful hematopoietic stem cell transplantation, ongoing progression of gastrointestinal manifestations can be life-threatening in TTC7A-deficient patients. OBJECTIVE: We sought to identify whether TTC7A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29775636
DOI: 10.1016/j.jaci.2018.02.057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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