Article

An FGF7-FGFR2-KLF4 feedback loop sustains anti-inflammatory signaling in epithelial cells

2026-03-23

Abstract excerpt

<h4>ABSTRACT</h4> Chronic or excessive inflammation are hallmarks of many human diseases, but the endogenous factors that limit inflammatory responses are insufficiently characterized. We discovered a broad anti-inflammatory function of fibroblast growth factor 7 (FGF7), which is mediated via epithelial cels. FGF7 suppressed the expression of pro-inflammatory and immunomodulatory genes in cultured human keratinoc...

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Literature Corpus work: 6f78e31a-99e8-55fd-aa3c-320d185f9981
DOI: 10.64898/2026.03.20.711763

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