Bdnf variant is associated with milder motor symptom severity in early-stage Parkinson's disease.

doi:10.1016/j.parkreldis.2018.05.003

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Article

Bdnf variant is associated with milder motor symptom severity in early-stage Parkinson's disease.

Parkinsonism & related disorders - 1 Aug 2018

Fischer D Luke, Auinger Peggy, Goudreau John L, Paumier Katrina L, Cole-Strauss Allyson, Kemp Christopher J, Lipton Jack W, Sortwell Caryl E

Abstract excerpt

INTRODUCTION: Parkinson's disease (PD) progression is heterogeneous. Variants in PD-related genes may alter disease progression or severity. We examined if the single nucleotide variant rs6265 in the gene Bdnf alters clinical phenotype in early-stage, unmedicated PD. METHODS: A retrospective analysis was conducted using data collected in the Deprenyl And Tocopherol Antioxidative Therapy Of Parkinsonism (DATATOP)...

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PMID: 29759928
DOI: 10.1016/j.parkreldis.2018.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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