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Article

BDNF rs6265 Variant Alters Outcomes with Levodopa in Early-Stage Parkinson's Disease.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics - 1 Oct 2020

Fischer D Luke, Auinger Peggy, Goudreau John L, Cole-Strauss Allyson, Kieburtz Karl, Elm Jordan J, Hacker Mallory L, Charles P David, Lipton Jack W, Pickut Barbara A, Sortwell Caryl E

Abstract excerpt

Disease outcomes are heterogeneous in Parkinson's disease and may be predicted by gene variants. This study investigated if the BDNF rs6265 single nucleotide polymorphism (SNP) is associated with differential outcomes with specific pharmacotherapy treatment strategies in the "NIH Exploratory Trials in PD Long-term Study 1" (NET-PD LS-1, n = 540). DNA samples were genotyped for the rs6265 SNP and others...

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Identifiers

PMID: 33215284
DOI: 10.1007/s13311-020-00965-9
PMCID: PMC7851242

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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