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Article

BDNF val66met influences time to onset of levodopa induced dyskinesia in Parkinson's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 Feb 2009

Foltynie T, Cheeran B, Williams-Gray C H, Edwards M J, Schneider S A, Weinberger D, Rothwell J C, Barker R A, Bhatia K P

Abstract excerpt

BACKGROUND: Levodopa induced dyskinesias (LID) are a common problem which ultimately limit the effective treatment of patients with Parkinson's disease (PD). There is accumulating evidence that LID develop due to abnormal synaptic plasticity, which is in turn influenced by the release of brain de...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18977816
DOI: 10.1136/jnnp.2008.154294

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18977816-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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BDNF val66met influences time to onset of levodopa induced dyskinesia in Parkinson's disease.PMID 18977816Read ↗

Influence of single nucleotide polymorphisms in COMT, MAO-A and BDNF genes on dyskinesias and levodopa use in Parkinson's disease.Semantic proximity Read ↗

Gene polymorphisms and motor levodopa-induced complications in Parkinson's disease.Semantic proximity Read ↗

BDNF genetic variants are associated with onset age of familial Parkinson disease: GenePD Study.Semantic proximity Read ↗

Association between the Val66Met (rs6265) polymorphism of the brain-derived neurotrophic factor (BDNF) gene, BDNF protein level in the blood and the risk of developing early‑onset Parkinson's disease.Semantic proximity Read ↗

Sequence variants in SLC6A3, DRD2, and BDNF genes and time to levodopa-induced dyskinesias in Parkinson's disease.Semantic proximity Read ↗

Plasma Brain-Derived Neurotrophic Factor Levels, Brain-Derived Neurotrophic Factor Val66Met Polymorphism, and Their Association with Phenoconversion in Isolated REM Sleep Behavior Disorder.Semantic proximity Read ↗

Val66Met BDNF polymorphism is associated with Parkinson's disease cognitive impairmentSemantic proximity Read ↗

BDNF G196A (Val66Met) polymorphism associated with cognitive impairment in Parkinson's disease.Semantic proximity Read ↗

BDNF rs6265 Variant Alters Outcomes with Levodopa in Early-Stage Parkinson's Disease.Semantic proximity Read ↗

Bdnf variant is associated with milder motor symptom severity in early-stage Parkinson's disease.Semantic proximity Read ↗

The role of genetic factors in the occurrence of levodopa-induced motor complications in Parkinson's disease.Semantic proximity Read ↗

Dopamine receptors and BDNF-haplotypes predict dyskinesia in Parkinson's diseaseSemantic proximity Read ↗

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