Article
TLR4 gene polymorphisms rs11536889 is associated with intracranial aneurysm susceptibility.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Jul 2018
Liu Liang, Zhang Qin, Xiong Xiao-Yi, Gong Qiu-Wen, Liao Mao-Fan, Yang Qing-Wu
Abstract excerpt
Intracranial aneurysm (IA) is a common lesion which often present asymptomatic until the time of rupture and result in subarachnoid hemorrhage (SAH). The pathogenesis of IA formation is complex and is influenced by both genetic and environmental risk factors. For exploring the detailed molecular and cellular mechanisms involved in the pathogenesis of IA, recent studies indicated inflammatory pathways and their...
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