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Article

TLR4 rs1927914 polymorphism contributes to serum TLR4 levels in patients with aortic aneurysm.

Experimental and molecular pathology - 1 Apr 2021

Li Tan, Jing Jingjing, Dong Nannan, Liu Xiaozheng, Ma Chunyan, Yang Jun

Abstract excerpt

Toll-like receptor 4 (TLR4) is a crucial regulator of inflammatory reactions and vascular remodeling. Elevated TLR4 expression has been proved to be correlated with an increased risk of aortic aneurysm (AA). This study aimed to explore the influence of TLR4 gene polymorphisms on TLR4 expression levels and its probable functional significance in AA disease. A total of 294 AA patients and 285 controls were enrolled...

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Identifiers

PMID: 33516663
DOI: 10.1016/j.yexmp.2021.104609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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