Article
Associations between Toll-like receptor 4 Asp299Gly polymorphism and susceptibility to intracranial aneurysm among male and female patients within the North Indian population.
Neurological research - 1 Jan 2025
Singh Anjali, Maurya Ved Prakash, Dewangan Ritu, Singh Mayank, Srivastava Arun Kumar, Kumar Alok
Abstract excerpt
OBJECTIVES: Intracranial aneurysms (IA), often remain asymptomatic until they get ruptured, invariably leads to subarachnoid hemorrhage (SAH), and is influenced by both genetic and environmental factors. Recent studies indicated inflammation as a key player in IA development. This study delves into genetic variations within inflammatory pathways, focusing on TLR4-mediated cytokine release as potential IA...
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