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Article

Implementation of next generation sequencing technology for somatic mutation detection in routine laboratory practice.

Pathology - 1 Jun 2018

Giardina Tindaro, Robinson Cleo, Grieu-Iacopetta Fabienne, Millward Michael, Iacopetta Barry, Spagnolo Dominic, Amanuel Benhur

Abstract excerpt

The introduction of next generation sequencing (NGS) in the routine diagnostic setting is still in the development phase and has been limited by its complexity. Targeted NGS offers an attractive alternative to performing multiple single target assays and is very useful in meeting the increasing clinical demand for testing of multiple genetic aberrations in cancer specimens. To this end, we carried out a blinded...

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Identifiers

PMID: 29752127
DOI: 10.1016/j.pathol.2018.01.005

Genes

CAST
EGFR
KIT

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