Article
Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.
International journal of molecular medicine - 1 May 2022
Chevrier Sandy, Brasselet Astrid, Carnet Marion, Chevriaux Angélique, Gibeaud Anne, Jourdain Marine, Mananet Hugo, Truntzer Caroline, Beltjens Françoise, Charon-Barra Céline, Arnould Laurent, Albuisson Juliette, Comte Anthony, Derangère Valentin, Goussot Vincent, Boidot Romain
Abstract excerpt
Molecular testing is extremely important in cancer care, starting as early as at diagnosis. In order to address the challenge of providing reliable results within the timeframe adapted to patient management and suitable to guide clinical decisions, a capture‑based next‑generation sequencing (NGS) panel focusing on ten genes known to harbor genetic variations which may be targeted by approved drugs in patients...
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