Article
Next-generation sequencing and molecular therapy.
Clinical medicine (London, England) - 1 Jan 2023
Morton Cienne, Sarker Debashis, Ross Paul
Abstract excerpt
Cancers contain a plethora of mutations, few of which are critical to maintaining a state of malignancy. With our ever-expanding understanding of the genomic complexity of cancer, potentially actionable biomarkers whose inhibition could cripple cancer growth are increasingly being elucidated. Modern cancer drug development has largely switched from cytotoxic agents to targeted therapies and immunotherapy, with...
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