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Next generation sequencing: clinical applications in solid tumours

3 Nov 2017

Abstract excerpt

Next generation sequencing (NGS) has unravelled the genetic alterations that underlie the pathogenesis of cancer. It is now becoming integrated into routine clinical diagnostics of malignant tumours. NGS supports diagnosis, identifies therapeutic targets, reveals resistance mechanisms and facilitates disease monitoring. It takes a central function in the implementation of cancer therapies adapted to the molecular...

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PMID: 29250205
DOI: 10.1007/s12254-017-0361-1

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