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Article

Technical and implementation issues in using next-generation sequencing of cancers in clinical practice.

British journal of cancer - 20 Aug 2013

Ulahannan D, Kovac M B, Mulholland P J, Cazier J-B, Tomlinson I

Abstract excerpt

Next-generation sequencing (NGS) of cancer genomes promises to revolutionise oncology, with the ability to design and use targeted drugs, to predict outcome and response, and to classify tumours. It is continually becoming cheaper, faster and more reliable, with the capability to identify rare yet clinically important somatic mutations. Technical challenges include sequencing samples of low quality and/or...

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Identifiers

PMID: 23887607
DOI: 10.1038/bjc.2013.416
PMCID: PMC3749581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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