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Article

Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy.

BMC cancer - 11 May 2018

Limviphuvadh Vachiranee, Tan Chee Seng, Konishi Fumikazu, Jenjaroenpun Piroon, Xiang Joy Shengnan, Kremenska Yuliya, Mu Yar Soe, Syn Nicholas, Lee Soo Chin, Soo Ross A, Eisenhaber Frank, Maurer-Stroh Sebastian, Yong Wei Peng

Abstract excerpt

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) can influence patient outcome such as drug response and toxicity after drug intervention. The purpose of this study is to develop a systematic pathway approach to accurately and efficiently predict novel non-synonymous SNPs (nsSNPs) that could be causative to gemcitabine-based chemotherapy treatment outcome in Singaporean non-small cell lung cancer (NSCLC)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29751792
DOI: 10.1186/s12885-018-4471-x
PMCID: PMC5948914

Genes

ABCG2

Variants

rs2231142
rs2231142
rs2231142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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