Article
Potentially functional genetic variants in PLIN2, SULT2A1 and UGT1A9 genes of the ketone pathway and survival of nonsmall cell lung cancer.
International journal of cancer - 15 Sept 2020
Tang Dongfang, Zhao Yu C, Liu Hongliang, Luo Sheng, Clarke Jeffrey M, Glass Carolyn, Su Li, Shen Sipeng, Christiani David C, Gao Wen, Wei Qingyi
Abstract excerpt
The ketone metabolism pathway is a principle procedure in physiological homeostasis and induces cancer cells to switch between glycolysis and oxidative phosphorylation for energy production. We conducted a two-phase analysis for associations between genetic variants in the ketone metabolism pathway genes and survival of nonsmall cell lung cancer (NSCLC) by analyzing genotyping data from two published genome-wide...
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