Article
Genes associated with genotype-specific DNA methylation in squamous cell carcinoma as candidate drug targets.
BMC systems biology - 1 Jan 2014
Kinoshita Ryoichi, Iwadate Mitsuo, Umeyama Hideaki, Taguchi Y-h
Abstract excerpt
BACKGROUND: Aberrant DNA methylation is often associated with cancers. Thus, screening genes with cancer-associated aberrant DNA methylation is a useful method to identify candidate cancer-causing genes. Aberrant DNA methylation is also genotype dependent. Thus, the selection of genes with genotype-specific aberrant DNA methylation in cancers is potentially important for tailor-made medicine. The selected genes...
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