Article
Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls.
Human genetics - 1 May 2013
Brenner Darren R, Brennan Paul, Boffetta Paolo, Amos Christopher I, Spitz Margaret R, Chen Chu, Goodman Gary, Heinrich Joachim, Bickeböller Heike, Rosenberger Albert, Risch Angela, Muley Thomas, McLaughlin John R, Benhamou Simone, Bouchardy Christine, Lewinger Juan Pablo, Witte John S, Chen Gary, Bull Shelley, Hung Rayjean J
Abstract excerpt
Recent evidence suggests that inflammation plays a pivotal role in the development of lung cancer. In this study, we used a two-stage approach to investigate associations between genetic variants in inflammation pathways and lung cancer risk based on genome-wide association study (GWAS) data. A t...
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