Article
Association study between genetic variations in Axin2 gene and lung cancer risk in North Indian population: A multiple interaction analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2017
Bahl Charu, Sharma Siddharth, Singh Navneet, Behera Digamber
Abstract excerpt
Wnt pathway has been implicated in the process of human carcinogenesis. Axis inhibition protein2 ( Axin2), a major scaffold protein is an antagonist of Wnt pathway and is potent to act as a tumor suppressor gene in various human cancers. Therefore, the seven polymorphic sites of Axin2 gene were analyzed, in relation to lung cancer susceptibility in North Indians. A total of 608 subjects were genotyped using...
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