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Clinical relevance of genetic polymorphisms in WNT signaling pathway (SFRP1, WNT3A, CTNNB1, WIF-1, DKK-1, LRP5, LRP6) on pulmonary tuberculosis in a Chinese population.

Frontiers in immunology - 1 Jan 2022

Huang Qian, Wang Chao-Cai, Liu Yun-Guang, Zhao Chang-Ming, Zhang Tian-Ping, Liu Yan, Wang Hua

Abstract excerpt

The present study was performed to evaluate the association of WNT signaling pathway genes variants with pulmonary tuberculosis (PTB) risk in Chinese Han population. Our study subjects were composed of 452 PTB patients and 465 normal controls, and seventeen SNPs of seven genes in WNT signaling pathway (SFRP1, WNT3A, CTNNB1, WIF-1, DKK-1, LRP5, LRP6) were genotyped by SNPscan technique. We found no significant...

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Identifiers

PMID: 36569862
DOI: 10.3389/fimmu.2022.1011700
PMCID: PMC9768481

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