Article
Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.
Environmental and molecular mutagenesis - 1 May 2009
Shen Min, Vermeulen Roel, Rajaraman Preetha, Menashe Idan, He Xingzhou, Chapman Robert S, Yeager Meredith, Thomas Gilles, Burdett Laurie, Hutchinson Amy, Yuenger Jeff, Chanock Stephen, Lan Qing
Abstract excerpt
The high incidence of lung cancer in Xuanwei County, China has been attributed to exposure to indoor smoky coal emissions that contain polycyclic aromatic hydrocarbons (PAHs). The inflammatory response induced by coal smoke components may promote lung tumor development. We studied the association between single nucleotide polymorphisms (SNPs) in genes involved in innate immunity and lung cancer risk in a...
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