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Article

αT-catenin: A developmentally dispensable, disease-linked member of the α-catenin family

3 Apr 2018

Abstract excerpt

α-Catenins are actin-filament binding proteins and critical subunits of the cadherin-catenin cell-cell adhesive complex. They are found in nominally-defined epithelial (E), neural (N), and testis (T) forms transcribed from three distinct genes. While most of α-catenin research has focused on the developmentally essential founding member, αE-catenin, this review discusses recent studies on αT-catenin (CTNNA3), a...

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PMID: 29746206
DOI: 10.1080/21688370.2018.1463896

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