Article
Generation and comparative genomics of synthetic dengue viruses.
BMC bioinformatics - 8 May 2018
Goz Eli, Tsalenchuck Yael, Benaroya Rony Oren, Zafrir Zohar, Atar Shimshi, Altman Tahel, Julander Justin, Tuller Tamir
Abstract excerpt
BACKGROUND: Synthetic virology is an important multidisciplinary scientific field, with emerging applications in biotechnology and medicine, aiming at developing methods to generate and engineer synthetic viruses. In particular, many of the RNA viruses, including among others the Dengue and Zika, are widespread pathogens of significant importance to human health. The ability to design and synthesize such viruses...
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