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Article

Tracking the evolution of dengue virus strains D2S10 and D2S20 by 454 pyrosequencing.

PloS one - 1 Jan 2013

Makhluf Huda, Buck Michael D, King Kevin, Perry Stuart T, Henn Matthew R, Shresta Sujan

Abstract excerpt

Dengue virus is the most prevalent mosquito-borne virus worldwide. In this study, we used pyrosequencing to analyze the whole viral genome of two mouse-adapted strains, D2S10 and D2S20, that induce a dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS)-like lethal disease in mice lacking the type I and/or type II interferon receptors. Previous experiments with D2S10 indicated that N124D and K128E mutations in...

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Identifiers

PMID: 23342105
DOI: 10.1371/journal.pone.0054220
PMCID: PMC3544829

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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