Article
Generation and characterization of genetically and antigenically diverse infectious clones of dengue virus serotypes 1-4.
Emerging microbes & infections - 1 Dec 2022
Tamura Tomokazu, Zhang Jiayu, Madan Vrinda, Biswas Abhishek, Schwoerer Michael P, Cafiero Thomas R, Heller Brigitte L, Wang Wei, Ploss Alexander
Abstract excerpt
Dengue is caused by four genetically distinct viral serotypes, dengue virus (DENV) 1-4. Following transmission by Aedes mosquitoes, DENV can cause a broad spectrum of clinically apparent disease ranging from febrile illness to dengue hemorrhagic fever and dengue shock syndrome. Progress in the understanding of different dengue serotypes and their impacts on specific host-virus interactions has been hampered by...
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