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Reverse genetics systems for SARS-CoV-2: Development and applications

11 Oct 2023

Abstract excerpt

The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused serious harm to human health and struck a blow to global economic development. Research on SARS-CoV-2 has greatly benefited from the use of reverse genetics systems, which have been established to artificially manipulate the viral genome, generating recombinant and reporter infectious viruses or biosafety level 2...

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PMID: 37832720
DOI: 10.1016/j.virs.2023.10.001

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