Article
A Synthetic Porcine Reproductive and Respiratory Syndrome Virus Strain Confers Unprecedented Levels of Heterologous Protection.
Journal of virology - 1 Dec 2015
Vu Hiep L X, Ma Fangrui, Laegreid William W, Pattnaik Asit K, Steffen David, Doster Alan R, Osorio Fernando A
Abstract excerpt
UNLABELLED: Current vaccines do not provide sufficient levels of protection against divergent porcine reproductive and respiratory syndrome virus (PRRSV) strains circulating in the field, mainly due to the substantial variation of the viral genome. We describe here a novel approach to generate a PRRSV vaccine candidate that could confer unprecedented levels of heterologous protection against divergent PRRSV...
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