Article
Comparison of Genotypic and Phenotypic Correlations: Cheverud's Conjecture in Humans.
Genetics - 1 Jul 2018
Sodini Sebastian M, Kemper Kathryn E, Wray Naomi R, Trzaskowski Maciej
Abstract excerpt
Accurate estimation of genetic correlation requires large sample sizes and access to genetically informative data, which are not always available. Accordingly, phenotypic correlations are often assumed to reflect genotypic correlations in evolutionary biology. Cheverud's conjecture asserts that the use of phenotypic correlations as proxies for genetic correlations is appropriate. Empirical evidence of the...
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