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Article

Populations, Traits, and Their Spatial Structure in Humans.

Genome biology and evolution - 1 Dec 2021

Sohail Mashaal, Izarraras-Gomez Alan, Ortega-Del Vecchyo Diego

Abstract excerpt

The spatial distribution of genetic variants is jointly determined by geography, past demographic processes, natural selection, and its interplay with environmental variation. A fraction of these genetic variants are "causal alleles" that affect the manifestation of a complex trait. The effect exerted by these causal alleles on complex traits can be independent or dependent on the environment. Understanding the...

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PMID: 34894236
DOI: 10.1093/gbe/evab272
PMCID: PMC8715524

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