Article
A functional promoter polymorphism in interleukin 12B gene is associated with an increased risk of ovarian endometriosis.
Gene - 5 Aug 2018
Zhao Wei, Li Yan, Zhao Jian, Kang Shan
Abstract excerpt
OBJECTIVE: To explore the role of functional genetic variant of IL12B in the pathogenesis of ovarian endometriosis. STUDY DESIGN: This study included 815 patients with ovarian endometriosis and 788 women in the control group. Two polymorphisms were genotyped by a method of polymerase chain reaction and ligase detection reaction. To assess the biological significance of polymorphisms, we detected the level of...
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