Article
Genetic variants in the IL12B gene are associated with inflammatory bowel diseases in the Korean population.
Journal of gastroenterology and hepatology - 1 Oct 2013
Moon Chang Mo, Shin Dong-Jik, Son Nak-Hoon, Shin Eun-Soon, Hong Sung Pil, Kim Tae Il, Kim Won Ho, Cheon Jae Hee
Abstract excerpt
BACKGROUND AND AIM: Recent genomic studies have identified genetic variants in the IL12B gene, which encodes the p40 subunit shared by interleukin 12 and interleukin 23, as susceptibility loci for inflammatory bowel disease (IBD). The study aimed to identify additional novel genetic variants in IL12B and investigated whether variants confer susceptibility to the development of Crohn's disease (CD) or ulcerative...
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