A Functional Polymorphism in the Promoter Region of Interleukin-12B Increases the Risk of Colorectal Cancer.

doi:10.1155/2020/2091781

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Article

A Functional Polymorphism in the Promoter Region of Interleukin-12B Increases the Risk of Colorectal Cancer.

BioMed research international - 1 Jan 2020

Liu Yabin, Li Binghui, Wang Lili, Kong Dexian

Abstract excerpt

OBJECTIVE: To investigate whether the polymorphisms of interleukin-12B (IL-12B) were associated with the risk of developing colorectal cancer (CRC). Patients and Methods. Genotypes of rs17860508 and rs3212227 were determined by polymerase chain reaction with a direct sequencing method in 329 CRC patients and 342 matched healthy control subjects. The expression of IL-12B) were associated with the risk of...

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PMID: 32149085
DOI: 10.1155/2020/2091781
PMCID: PMC7054766

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