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Article

Association between gene polymorphisms of IL-12, IL-12 receptor and IL-27 and organ involvement in Iranian endometriosis patients.

International journal of immunogenetics - 1 Feb 2023

Zare Maryam, Hesampour Fatemeh, Poordast Tahereh, Valibeigi Maryam, Enayatmehri Maliheh, Ahmadi Sahar, Nasri Fatemeh, Gharesi-Fard Behrouz

Abstract excerpt

Endometriosis is an inflammatory disease characterized by the presence of ectopic endometrial tissue, immune cell dysfunction and abnormal cytokine secretion. In addition to immunological factors, genetic variations that influence endometriosis severity and cytokine expression levels play important roles in the pathogenesis of this disease. Interleukin-12 (IL-12), specifically its p40 subunit encoded by IL-12B...

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PMID: 36328955
DOI: 10.1111/iji.12606

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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