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Article

The association between interleukin-10 (IL-10) -592C/A, -819T/C, -1082G/A promoter polymorphisms and endometriosis.

Archives of gynecology and obstetrics - 1 Feb 2017

Malutan Andrei Mihai, Drugan Cristina, Walch Katharina, Drugan Tudor, Ciortea Razvan, Mihu Dan

Abstract excerpt

PURPOSE: Endometriosis has an incidence reaching up to 50% in infertile women. Cytokine-mediated immune responses seem to play an important role in endometriosis pathogenesis, but still the etiology and pathophysiology remain unclear. In the current study we tried to investigate whether there is a relationship between IL-10 genetic polymorphism, serum levels of IL-10 and the presence of advanced endometriosis....

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PMID: 28004192
DOI: 10.1007/s00404-016-4269-5

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