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Article

The nuclear factor-kB functional promoter polymorphism is associated with endometriosis and infertility.

Human immunology - 1 Nov 2012

Bianco Bianca, Lerner Tatiana G, Trevisan Camila Martins, Cavalcanti Viviane, Christofolini Denise M, Barbosa Caio P

Abstract excerpt

INTRODUCTION: An aberrant immunologic mechanism has been suggested to be involved in the pathogenesis of endometriosis. Nuclear factor-kB (NF-kB) plays a key role in the immune and inflammatory response and modulates cell proliferation, apoptosis, adhesion, invasion, and angiogenesis in many cell types involved in the development of endometriosis. We hypothesized a possible relationship between the NFKB1 promoter...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to NF-kappa B p50 Subunit

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 22902396
DOI: 10.1016/j.humimm.2012.08.008

Genes

NFKB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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