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Article

Influence of interleukin-8 polymorphism on endometriosis-related pelvic pain.

Human immunology - 1 Oct 2023

Cardoso Jéssica Vilarinho, Machado Daniel Escorsim, da Silva Mayara Calixto, de Mello Matheus Pereira, Berardo Plinio Tostes, Medeiros Rui, Perini Jamila Alessandra

Abstract excerpt

Endometriosis presents a pro-inflammatory microenvironment influenced by cytokines, such as interleukin (IL)-8, which expression may be influenced by genetic polymorphisms. Therefore, we aimed to investigate the role of interleukin (IL)-8 rs4073 polymorphism in endometriosis' development and its related symptoms. A case-control study was conducted with 207 women with endometriosis and 193 healthy controls....

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PMID: 37468423
DOI: 10.1016/j.humimm.2023.07.004

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