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Article

Antiproliferative Effects of Epigenetic Modifier Drugs Through E-cadherin Up-regulation in Liver Cancer Cell Lines.

Annals of hepatology - 1 Jan 2000

Uribe Diego, Cardona Andres, Esposti Davide Degli, Cros Marie-Pierre, Cuenin Cyrille, Herceg Zdenko, Camargo Mauricio, Cortés-Mancera Fabian M

Abstract excerpt

INTRODUCTION AND AIM: Epigenetic alterations play an essential role in cancer onset and progression, thus studies of drugs targeting the epigenetic machinery are a principal concern for cancer treatment. Here, we evaluated the potential of the combination of the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine (5aza-dC) and the pan-deacetylase inhibitor Trichostatin A (TSA), at low cytotoxic concentrations,...

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Source

Identifiers

PMID: 29735783
DOI: 10.5604/01.3001.0011.7389

Genes

CDH1
CTNNB1
DKK3
SFRP1
WIF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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