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Article

HMGA 2 promotes glioma invasion and poor prognosis via a long‐range chromatin interaction

7 May 2018

Abstract excerpt

To identify the function and underlying mechanisms of HMGA2 on the prognosis and invasion of gliomas, HMGA2 was detected by immunohistochemistry. The Kaplan-Meier and Cox's regression analysis results showed that higher HMGA2 level predicted the poorer outcomes of glioma patients. ChIP-qPCR, DNA electrophoretic mobility shift assay, chromosome conformation capture, and co-immunoprecipitation were applied to...

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PMID: 29733521
DOI: 10.1002/cam4.1534

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